In his discussion about signs of the end of this age, Jesus told his disciples they would not only face opposition, but would be betrayed by their own family members. He said, “But when they shall lead you, and deliver you up. Take no thought beforehand what ye shall speak, neither do ye premeditate: but whatsoever shall be given you in that hour, that speak ye: for it is not ye that speak, but the Holy Ghost. Now the brother shall betray the brother to death, and the father the son; and children shall rise up against parents, and shall cause them to be put to death. And ye shall be hated of all men for my name’s sake: but he that shall endure unto the end, the same shall be saved” (Mark 13:11-13). Jesus wasn’t suggesting that endurance was a requirement for salvation, but rather that perseverance was an indicator of salvation (note on Mark 13:13). Paul wrote about this in his epistle to the Hebrews where he said, “For we are made partakers of Christ, if we hold the beginning of our confidence stedfast to the end. Whilst it is said, To day if ye will hear his voice, harden not your hearts, as in the provocation” (Hebrew 3:14-15).
Jesus understood that the severe trials the early Christians would face would be more than some of them could handle. His encouragement to endure to the end may have had a twofold meaning. First, that the individual Christians wouldn’t let the threat of persecution prevent them from receiving salvation and second, that the united body of believers that is sometimes referred to as Christ’s church, would continue to preach the gospel until Jesus’ return. In the midst of his message about the betrayal of Christians, Jesus referred to a prophecy that is found in the book of Daniel. He said, “When ye therefore shall see the abomination of desolation, spoken of by Daniel the prophet, stand in the holy place, (whoso readeth, let him understand:) then let them that be in Judea flee into the mountains: let him which is on the housetop not come down to take any thing out of his house: neither let him which is in the field return back to take his clothes” (Matthew 24:15-18). Daniel’s prophecy is thought to be a sign of the Antichrist outlawing worship of God during the Great Tribulation (note on Daniel 9:25-27). If so, then Jesus may have been suggesting that the betrayal of Christians would reach its climax at that point and it would no longer be safe for his followers to identify themselves.
Jesus’ reference to the Great Tribulation was probably meant for Jewish believers only. Many Bible Scholars believe that Christians will be removed from the earth before the Great Tribulation begins. Jesus indicated that after the abomination of desolation is set up in God’s temple, “then shall be great tribulation, such as was not since the beginning of the world to this time, no, nor ever shall be. And except those days should be shortened, there should no flesh be saved: but for the elect’s sake those days shall be shortened” (Matthew 24:21-22). In spite of extreme persecution and betrayal by their loved ones, many Jews will turn to Christ during the Great Tribulation. It is likely that the work Jesus started with the original twelve Jewish apostles will be revived in some form during that time period. The Apostle John indicated 144,000 Jews would be preserved, 12,000 each from all the tribes of Israel during the Great Tribulation. These Jewish believers will be killed for their faith and given a special reward for their suffering (Revelation 7:13-17). At the end of the Great Tribulation, they will live and reign with Christ for a thousand years (Revelation 20:4).